The Research Institute carries out the initiative topic “Development of effective methods for the synthesis of new heterocyclic derivatives of some alkaloids with a wide range of biological activity” under the guidance of Professor of the Department of Ch&ChT Ibraev M.K.
The aim of the work is to develop effective methods for the synthesis of nitrogen-containing heterocyclic compounds based on natural substances with biological action.
The results of the work and their novelty consist in the development of methods for obtaining and optimal conditions for the synthesis of pyrazoline and oxazoline derivatives under the conditions of classical synthesis, microwave and ultrasonic activation, as well as computer bioscreening of synthesized substances.
The developed methods for obtaining potentially biologically active azoles are recommended for the development of new biologically active substances and practical application in the synthesis of these classes of compounds.
The significance of the work lies in the development of optimal methods for the synthesis of new substances, the establishment of their structure and testing of their biological activity.